Modifiers of Cardiac Phenotypes.
نویسنده
چکیده
منابع مشابه
Cardiac conduction defects and Brugada syndrome: A family with overlap syndrome carrying a nonsense SCN5A mutation☆
BACKGROUND Phenotypes often differ even within family members carrying the same SCN5A mutation. We aimed to evaluate the genetic modifiers in a family with Brugada syndrome (BrS) and sick sinus syndrome (SSS) with an SCN5A mutation that causes the truncated alpha-subunit of cardiac Na channel protein. METHODS To detect the genetic modifiers, we performed targeted panel sequencing of the codin...
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ورودعنوان ژورنال:
- Circulation. Cardiovascular genetics
دوره 8 3 شماره
صفحات -
تاریخ انتشار 2015